Diffusion-weighted MR findings in a reversible case of acute Wernicke encephalopathy

Acta Neurol Scand. 2001 Sep;104(3):178-81. doi: 10.1034/j.1600-0404.2001.00098.x.


We report a case of acute Wernicke encephalopathy (WE) in which apparent diffusion coefficient maps showed areas of increased diffusion in the bilateral medial thalami that corresponded to the hyperintense lesions on T2-weighted imaging. The hyperintense lesions on T2-weighted imaging disappeared with full recovery from symptoms. These findings suggest that the hyperintense lesions of the acute changes of WE include reversible vasogenic edema and are not caused by acute ischemia.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Aplastic / complications
  • Anemia, Aplastic / diagnosis
  • Brain / pathology
  • Brain Edema / diagnosis
  • Child, Preschool
  • Diagnosis, Differential
  • Diffusion
  • Female
  • Humans
  • Image Enhancement*
  • Magnetic Resonance Imaging*
  • Thalamus / pathology
  • Wernicke Encephalopathy / diagnosis*