In this paper we demonstrate how discrete event simulation technique can be used to optimise the use of catheterization capacity. The patient flow at the catheterization room is described. A simulation model of the current situation was built in MedModel, a discrete event simulation package, and the model was validated. A short presentation of MedModel is given. To investigate alternative ways to optimise the use of the catheterization room three experiments were formulated, modelled and simulated. Two different scheduling strategies were applied to the current situation and the three experimental situations. The number of patients that can be treated and the duration of a working day were determined as measures of performance. The results of the simulation experiments are discussed. The results of these experiments give the management of the catheterization room valuable information how to optimise the use of the catheterization room.