The dual origin of vaginal epithelium

Am J Anat. 1975 Jul;143(3):387-92. doi: 10.1002/aja.1001430309.

Abstract

The absence of the cranial three-fifths of the vaginae of male mice carrying the gene, Testicular Feminization, provides strong support for the view that vaginal epithelium is of dual origin, the cranial three-fifths being of Mullerian in origin and the caudal two-fifths being derived from the urogenital sinus.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Androgen-Insensitivity Syndrome
  • Androgens / pharmacology
  • Animals
  • Epithelial Cells
  • Estrogens / pharmacology
  • Female
  • Male
  • Mice
  • Mullerian Ducts / cytology
  • Sex Differentiation
  • Urethra / embryology
  • Urogenital System / embryology
  • Vagina / anatomy & histology
  • Vagina / embryology*

Substances

  • Androgens
  • Estrogens