Abstract
Bacterial and viral pathogens have evolved sophisticated strategies to manipulate the host cell's life span to their own advantage. This is achieved by modifications of the intrinsic apoptosis program at several checkpoints: kinases, caspases and mitochondria. The goal of this review is to give an overview over the molecular mechanisms involved.
MeSH terms
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Apoptosis*
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Bacteria / pathogenicity*
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Bacterial Infections / immunology
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Bacterial Infections / microbiology
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Bacterial Infections / physiopathology*
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Caspases / metabolism
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Humans
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Mitochondria / physiology
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Signal Transduction
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Virus Diseases / immunology
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Virus Diseases / physiopathology*
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Virus Diseases / virology
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Viruses / pathogenicity*