Symptomatic sinus node abnormalities following lithium carbonate therapy

Am J Med. 1975 Aug;59(2):285-7. doi: 10.1016/0002-9343(75)90365-4.


Symptomatic sinus node abnormalities occurred in a woman receiving lithium carbonate. Stimulation studies of the heart revealed that only the sinus node was affected. The abnormalities disappeared completely following cessation of lithium therapy.

MeSH terms

  • Arrhythmia, Sinus / chemically induced
  • Bipolar Disorder / drug therapy
  • Cardiac Catheterization
  • Female
  • Heart Atria
  • Heart Diseases / chemically induced*
  • Humans
  • Lithium / adverse effects*
  • Middle Aged
  • Pacemaker, Artificial
  • Sinoatrial Node / physiopathology*


  • Lithium