How the olfactory system makes sense of scents

Nature. 2001 Sep 13;413(6852):211-8. doi: 10.1038/35093026.


The human nose is often considered something of a luxury, but in the rest of the animal world, from bacteria to mammals, detecting chemicals in the environment has been critical to the successful organism. An indication of the importance of olfactory systems is the significant proportion - as much as 4% - of the genomes of many higher eukaryotes that is devoted to encoding the proteins of smell. Growing interest in the detection of diverse compounds at single-molecule levels has made the olfactory system an important system for biological modelling.

Publication types

  • Review

MeSH terms

  • Animals
  • Humans
  • Odorants
  • Olfactory Receptor Neurons / physiology
  • Pheromones / physiology
  • Signal Transduction
  • Smell / physiology*
  • Vomeronasal Organ / physiology


  • Pheromones