Composition and antimicrobial activity of the essential oils of Micromeria cristata subsp. phrygia and the enantiomeric distribution of borneol

J Agric Food Chem. 2001 Sep;49(9):4300-3. doi: 10.1021/jf0105034.

Abstract

Water-distilled essential oils from herbal parts of Micromeria cristata (Hampe) Griseb. subsp. phrygia P. H. Davis (Endemic) (Lamiaceae) collected from three different localities were analyzed by GC-MS. The major component characterized in the three oils was borneol (27-39%). Other main components were determined as camphor (9-15%), caryophyllene oxide (4-6%), and trans-verbenol (4-6%) in the oils. Enantiomeric distributions of borneol and camphor in the oils were determined on a fused silica Lipodex-E capillary column using a multidimensional GC-MS system. The three essential oils and both enantiomers of borneol have been evaluated for their antimicrobial activity. They showed inhibitory effects on Gr (-) and Gr (+) pathogenic microorganisms.

MeSH terms

  • Camphanes
  • Colony Count, Microbial
  • Gas Chromatography-Mass Spectrometry
  • Gram-Negative Bacteria / drug effects*
  • Gram-Positive Bacteria / drug effects*
  • Lamiaceae / chemistry*
  • Microbial Sensitivity Tests
  • Oils, Volatile / analysis*
  • Oils, Volatile / pharmacology*

Substances

  • Camphanes
  • Oils, Volatile
  • isoborneol