Aphrodisiac evaluation in non-copulator male rats after chronic administration of Eurycoma longifolia Jack

Fundam Clin Pharmacol. 2001 Aug;15(4):265-8. doi: 10.1046/j.1472-8206.2001.00038.x.


The aphrodisiac effect of Eurycoma longifolia Jack (0.5 g/kg) was evaluated in noncopulator male rats using an electrical cage. Fractions of E. longifolia Jack decreased the hesitation time of noncopulator male rats, throughout the investigation period. Furthermore, it possessed a transient increase in the percentage of the male rats responding to the right choice, more than 50% of the male rats scored "right choice" after 3 weeks post-treatment and the effect became more prominent after 8 weeks post-treatment (only 40-50% of the control male rats responded to the right choice) using the electrical copulation cage. Hence, this study lends further support to the use of the plant by indigenous populations as a traditional medicine for its aphrodisiac property.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Aphrodisiacs / pharmacology*
  • Copulation / drug effects*
  • Copulation / physiology
  • Drug Evaluation, Preclinical / methods
  • Female
  • Glaucarubin / analogs & derivatives*
  • Glaucarubin / pharmacology*
  • Male
  • Plant Preparations / pharmacology
  • Quassins*
  • Rats
  • Rats, Sprague-Dawley


  • Aphrodisiacs
  • Plant Preparations
  • Quassins
  • eurycomanol
  • Glaucarubin