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Review
, 11 (18), R751-2

Fish Scale Development: Hair Today, Teeth and Scales Yesterday?

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Review

Fish Scale Development: Hair Today, Teeth and Scales Yesterday?

P T Sharpe. Curr Biol.

Abstract

A group of genes in the tumour necrosis factor signalling pathway are mutated in humans and mice with ectodermal dysplasias--a failure of hair and tooth development. A mutation has now been identified in one of these genes, ectodysplasin-A receptor, in the teleost fish Medaka, that results in a failure of scale formation.

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