Volume-controlled ventilation. Variations on a theme

Clin Perinatol. 2001 Sep;28(3):547-60, vi. doi: 10.1016/s0095-5108(05)70106-8.


Development of sophisticated transducers and microprocessor-based ventilators now enables the performance of volume-controlled ventilation of newborn infants. Volume-controlled modes include standard intermittent or synchronized intermittent mandatory ventilation; assist-control ventilation; and hybrid modes, such as pressure-support ventilation, pressure-regulated volume-control ventilation, volume-assured pressure support, and volume guarantee. This article describes the concepts and clinical applications of these ventilatory modes.

MeSH terms

  • Humans
  • Infant, Newborn
  • Respiration, Artificial / methods*
  • Respiratory Insufficiency / therapy
  • Ventilators, Mechanical