Abstract
We studied the expression of MUL, a gene encoding a novel member of the RING-B-Box-Coiled Coil family of zinc finger proteins that underlies the human inherited disorder, Mulibrey nanism. In early human and mouse embryogenesis MUL is expressed in dorsal root and trigeminal ganglia, liver and in epithelia of multiple tissues.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Dwarfism / genetics
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Epithelium / embryology
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Ganglia, Spinal / embryology
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Gene Expression Regulation, Developmental
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Humans
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In Situ Hybridization
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Liver / embryology
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Mice
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Nuclear Proteins / genetics*
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Trigeminal Ganglion / embryology
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Tripartite Motif Proteins
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Ubiquitin-Protein Ligases
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Zinc Fingers / genetics
Substances
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Nuclear Proteins
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Tripartite Motif Proteins
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TRIM37 protein, human
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Ubiquitin-Protein Ligases