Factors associated with the occurrence and magnitude of earthquake-induced increases in blood pressure

Am J Med. 2001 Oct 1;111(5):379-84. doi: 10.1016/s0002-9343(01)00832-4.


Background: Blood pressure increases transiently after a major earthquake, but the characteristics and the mechanism of this increase are unknown.

Methods: The study involved 124 elderly hypertensive outpatients from two clinics near the epicenter of the Hanshin-Awaji earthquake (7.2 on the Richter scale) for whom ambulatory blood pressure monitoring and assessment of end-organ damage had been performed before the earthquake.

Results: During the 1 to 2 weeks after the earthquake, while major aftershocks persisted, mean (+/- SD) systolic blood pressure was 14 +/- 16 mm Hg greater and mean diastolic blood pressure was 6 +/- 10 mm Hg greater, but these values returned to baseline by 3 to 5 weeks after the earthquake. The earthquake-induced increase in blood pressure correlated significantly with the "white coat" effect ([clinic systolic blood pressure minus 24-hour systolic blood pressure] r = 0.34, P <0.001), body mass index (r = 0.28, P <0.001), and age (r = 0.24, P <0.01). The earthquake-induced blood pressure increase was prolonged in patients with microalbuminuria for at least 2 months after the earthquake, whereas it was less pronounced in patients who had been treated with an alpha-blocker and in patients with diabetes mellitus.

Conclusions: These elderly patients with hypertension had a substantial increase in blood pressure after a major earthquake; the increase was usually transient, except in patients who had microalbuminuria. The correlation with white-coat hypertension suggests that both phenomena are related to sympathetic activation.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Analysis of Variance
  • Blood Pressure Determination
  • Disasters*
  • Female
  • Humans
  • Hypertension / epidemiology
  • Hypertension / physiopathology
  • Hypertension / psychology*
  • Japan / epidemiology
  • Linear Models
  • Male
  • Prospective Studies
  • Risk Factors
  • Stress, Psychological / physiopathology