An investigation on the use of removal-diffusion theory for BNCT treatment planning: a method for determining proper removal-diffusion parameters

Med Phys. 2001 Sep;28(9):1898-904. doi: 10.1118/1.1386424.

Abstract

This paper outlines a method for determining proper removal-diffusion parameters to be used in removal-diffusion theory calculations for the purpose of BNCT treatment planning. Additionally, this paper demonstrates that, given the proper choice of removal-diffusion parameters, removal-diffusion theory may provide an accurate calculation technique for determining absorbed dose distributions for the purpose of BNCT treatment planning. For a four-group, one-dimensional calculation in water, this method was used to determine values for the neutron scattering cross sections, neutron removal cross sections, neutron diffusion coefficients, and extrapolation distances. These values were then used in a one-dimensional DIF3D calculation. The results of the DIF3D calculation showed a maximum deviation of 2.5% from a MCNP calculation performed for the same geometry.

MeSH terms

  • Biophysical Phenomena
  • Biophysics
  • Boron Neutron Capture Therapy*
  • Brain Neoplasms / radiotherapy
  • Diffusion
  • Humans
  • Models, Theoretical
  • Monte Carlo Method
  • Neutrons
  • Radiotherapy Planning, Computer-Assisted / methods*
  • Radiotherapy Planning, Computer-Assisted / statistics & numerical data