Islands of linkage disequilibrium

Nat Genet. 2001 Oct;29(2):109-11. doi: 10.1038/ng1001-109.


A detailed knowledge of patterns of linkage disequilibrium in human populations is widely seen as a prerequisite for effective population-based disease gene mapping. New data suggest that linkage disequilibrium is highly structured into discrete blocks of sequence separated by hot spots of recombination.

Publication types

  • Comment
  • News

MeSH terms

  • Case-Control Studies
  • Genetics, Medical
  • Humans
  • Linkage Disequilibrium*
  • Recombination, Genetic