A two-component signal-transduction cascade in Carnobacterium piscicola LV17B: two signaling peptides and one sensor-transmitter

Peptides. 2001 Oct;22(10):1597-601. doi: 10.1016/s0196-9781(01)00494-6.

Abstract

In the lactic acid bacterium Carnobacterium piscicola LV17B a peptide-pheromone dependent quorum-sensing mode is involved in the regulation of bacteriocin production. Bacteriocin CB2 was identified as an environmental signal that induces bacteriocin production. Here, we demonstrate that a second 24 amino acid peptide (CS) also induces bacteriocin production. Transcription activation of several carnobacteriocin operons is triggered by CB2 or CS via a two-component signal transduction system composed of CbnK and CbnR.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / genetics*
  • Bacterial Proteins / metabolism
  • Bacteriocins / biosynthesis*
  • Bacteriocins / genetics*
  • Bacteriocins / metabolism
  • Genes, Regulator / genetics*
  • Lactobacillaceae
  • Operon / genetics
  • Peptides / genetics*
  • Peptides / metabolism*
  • Pheromones / genetics
  • Pheromones / metabolism
  • Plasmids / genetics
  • Promoter Regions, Genetic / drug effects
  • Promoter Regions, Genetic / genetics*
  • Signal Transduction / physiology

Substances

  • Bacterial Proteins
  • Bacteriocins
  • Peptides
  • Pheromones
  • bacteriocin B2 protein, Carnobacterium piscicola