Outcomes of a natural rubber latex control program in an Ontario teaching hospital

J Allergy Clin Immunol. 2001 Oct;108(4):628-33. doi: 10.1067/mai.2001.118792.


Background: Allergy to natural rubber latex (NRL) has been frequently reported in health care workers. However, there is little published evidence of the outcome of hospital intervention programs to reduce exposure and detect cases of sensitization early.

Objective: This study assesses the effects of intervention to reduce NRL allergy in an Ontario teaching hospital with approximately 8000 employees.

Methods: A retrospective review assessed annual numbers of employees visiting the occupational health clinic, allergy clinic, or both for manifestations of NRL allergy compared with the timing of introduction of intervention strategies, such as worker education, voluntary medical surveillance, and hospital conversion to low-protein, powder-free NRL gloves.

Results: The number of workers identified with NRL allergy rose annually, from 1 in 1988 to 6 in 1993. When worker education and voluntary medical surveillance were introduced in 1994, a further 25 workers were identified. Nonsterile gloves were changed to low-protein, powder-free NRL gloves in 1995: Diagnoses fell to 8 workers that year, and 2 of the 3 nurses who had been off work because of asthma-anaphylaxis were able to return to work with personal avoidance of NRL products. With a change to lower protein, powder-free NRL sterile gloves in 1997, allergy diagnoses fell to 3, and only 1 new case was identified subsequently up to May 1999. No increased glove costs were incurred as a result of consolidated glove purchases.

Conclusions: This program to reduce NRL allergy in employees was effectively achieved without additional glove costs while reducing expenses from time off work and workers' compensation claims.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Gloves, Protective / adverse effects*
  • Health Promotion
  • Hospitals, Teaching*
  • Incidence
  • Latex Hypersensitivity / epidemiology
  • Latex Hypersensitivity / prevention & control*
  • Occupational Exposure*
  • Ontario
  • Personnel, Hospital* / education
  • Population Surveillance
  • Program Evaluation
  • Rubber / adverse effects*


  • Rubber