The psychological impact of end-stage lung disease

Chest. 2001 Oct;120(4):1246-52. doi: 10.1378/chest.120.4.1246.


Study objectives: End-stage lung disease is associated with poor quality of life and increased risk for psychological distress. Despite the significant number of individuals with end-stage lung diseases, the emotional health of these patients, as compared with those with other chronic organ diseases, is not well-known. The purpose of this article is to elucidate personality styles and the presence of psychopathology in a clinical sample of patients with end-stage lung disease presenting for possible lung transplantation.

Design: Cross-sectional survey.

Setting: Two academic medical center transplant programs.

Participants: Two hundred forty-three consecutively referred transplant candidates.

Results: Cluster analysis of the Minnesota Multiphasic Personality Inventory (MMPI)-2 indicated five different personality styles. The majority of patients evidenced mild somatic and depressive symptoms. Approximately one fourth of the sample exhibited marked anxiety and mood disturbances. A small cluster also evidenced features consistent with an antisocial personality style.

Conclusions: Separate and distinct personality styles that could affect quality of life, the need for adjunct treatments, and medical compliance emerged from this sample of individuals with end-stage lung disease. Results are discussed in light of prior research on other end-stage organ conditions and in relation to personality and coping theories.

MeSH terms

  • Adaptation, Psychological
  • Adult
  • Aged
  • Anxiety / diagnosis
  • Anxiety / psychology*
  • Cross-Sectional Studies
  • Depression / diagnosis
  • Depression / psychology*
  • Female
  • Humans
  • Internal-External Control
  • Lung Transplantation / psychology
  • MMPI
  • Male
  • Middle Aged
  • Pulmonary Disease, Chronic Obstructive / psychology*
  • Pulmonary Disease, Chronic Obstructive / surgery
  • Quality of Life
  • Sick Role*