Perspectives on the integrative functions of the 'sympatho-adrenomedullary system'

Auton Neurosci. 2000 Oct 2;83(3):101-15. doi: 10.1016/S1566-0702(00)00171-5.


An historic survey is given of the gradual change of views and concepts concerning how the sympatho-adrenomedullary system is organized and operates: While it for nearly a century was considered to merely exhibit more or less generalized activation-inhibition responses, experimental studies during the last 50 years have revealed how it instead constitutes a highly sophisticated instrument for control, engaged in a variety of differentiated response patterns by which the brain controls events in major organ systems, down to include their cellular-molecular levels of organisation.

Publication types

  • Historical Article

MeSH terms

  • Adrenal Medulla / innervation*
  • Adrenal Medulla / physiology*
  • Animals
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System / innervation
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Neurosecretory Systems / growth & development
  • Neurosecretory Systems / physiology
  • Physiology / history*
  • Sympathetic Nervous System / physiology*
  • Vasomotor System / physiology