The balance of power in RNA trafficking

Curr Opin Neurobiol. 2001 Oct;11(5):558-63. doi: 10.1016/s0959-4388(00)00249-x.


In the past two years, several different RNA trafficking pathways have been characterized in oligodendrocytes; similar trafficking pathways have been discovered in neuronal and retroviral systems; co-assembly of multiple different RNAs into the same granules has been analyzed as a mechanism for coordinating gene expression; and a new hypothesis for RNA trafficking, based on the balance of power between kinesin and dynein in individual RNA granules, has been proposed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Heterogeneous-Nuclear Ribonucleoproteins
  • Humans
  • Oligodendroglia / physiology
  • Protein Transport / genetics*
  • Protein Transport / physiology
  • RNA / physiology*
  • Ribonucleoproteins / genetics
  • Ribonucleoproteins / physiology


  • Heterogeneous-Nuclear Ribonucleoproteins
  • Ribonucleoproteins
  • RNA