Genomic analysis of the Hsp70 superfamily in Arabidopsis thaliana

Cell Stress Chaperones. 2001 Jul;6(3):201-8. doi: 10.1379/1466-1268(2001)006<0201:gaoths>;2.


The Arabidopsis genome contains at least 18 genes encoding members of the 70-kilodalton heat shock protein (Hsp70) family, 14 in the DnaK subfamily and 4 in the Hsp110/SSE subfamily. While the Hsp70s are highly conserved, a phylogenetic analysis including all members of this family in Arabidopsis and in yeast indicates the homology of Hsp70s in the subgroups, such as those predicted to localize in the same subcellular compartment and those similar to the mammalian Hsp110 and Grp170. Gene structure and genome organization suggest duplication in the origin of some genes. The Arabidopsis hsp70s exhibit distinct expression profiles; representative genes of the subgroups are expressed at relatively high levels during specific developmental stages and under thermal stress.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis / genetics*
  • Arabidopsis / physiology
  • Arabidopsis Proteins / chemistry
  • Arabidopsis Proteins / genetics*
  • Arabidopsis Proteins / metabolism
  • Chromosome Mapping
  • Escherichia coli Proteins*
  • Gene Expression Regulation, Plant / physiology
  • Genes, Plant
  • Genome, Plant
  • HSP70 Heat-Shock Proteins / chemistry
  • HSP70 Heat-Shock Proteins / classification
  • HSP70 Heat-Shock Proteins / genetics*
  • HSP70 Heat-Shock Proteins / metabolism
  • Phylogeny
  • Protein Structure, Tertiary


  • Arabidopsis Proteins
  • Escherichia coli Proteins
  • HSP70 Heat-Shock Proteins
  • dnaK protein, E coli