Radiation-associated valvular heart disease in Hodgkin's disease is associated with characteristic thickening and fibrosis of the aortic-mitral curtain

J Heart Valve Dis. 2001 Sep;10(5):681-5.


Radiation-associated valvular dysfunction is characterized by variable aortic and mitral valve thickening. A review of three patients assessed echocardiographically revealed that radiation-associated valvular dysfunction after radiation treatment for Hodgkin's disease may be characterized by a unique and consistent pattern of thickening of the aortic and mitral valves involving the aortic-mitral curtain.

Publication types

  • Case Reports

MeSH terms

  • Aortic Valve / radiation effects*
  • Female
  • Heart Valve Diseases / etiology*
  • Heart Valve Diseases / mortality
  • Hodgkin Disease / complications*
  • Hodgkin Disease / mortality
  • Hodgkin Disease / radiotherapy*
  • Humans
  • Male
  • Middle Aged
  • Mitral Valve / radiation effects*
  • Radiation Pneumonitis / complications*
  • Radiation Pneumonitis / mortality
  • Treatment Failure