Human gene therapy: down the slippery slope?

Bioethics. 1993 Oct;7(5):402-19. doi: 10.1111/j.1467-8519.1993.tb00231.x.

Abstract

The strength of a slippery slope argument is a matter of some dispute. Some see it as a reasonable argument pointing out what probably or inevitably follows from adopting some practice, others see it as essentially a fallacious argument. However, there seems to be a tendency emerging to say that in many cases, the argument is not actually fallacious, although it may be unsubstantiated. I shall not try to settle this general discussion, but merely seek to assess the strength of the slippery slope argument applied to human gene therapy. The structure of my argument will be the following. First, I shall distinguish between three different versions of the slippery slope argument; two logical versions and an empirical one. Next, I will address human gene therapy in terms of each of the three versions, partly relying on slippery slope arguments against this practice that have already surfaced in the literature. I shall argue that neither version pulls through. The logical versions fail primarily because relevant distinctions can be made between different uses of gene therapy, contrary to what the proponents of the arguments claim. The empirical version fails because there seems to be no evidence supporting the claim that we shall in fact slide down the slope if we engage in gene therapy, and because if we accepted the conclusion that we should not allow gene therapy on the basis of the empirical argument, we should have to make very far-reaching and undesirable modifications in health care in general, in order to be consistent. Or at least so I shall argue.

MeSH terms

  • Altruism
  • Beneficence
  • Biomedical Technology
  • Ethics*
  • Eugenics
  • Genetic Diseases, Inborn
  • Genetic Engineering
  • Genetic Therapy*
  • Health
  • Health Care Rationing
  • Humans
  • Intelligence
  • Prejudice
  • Resource Allocation
  • Risk
  • Risk Assessment
  • Social Control, Formal
  • Social Justice
  • Social Values
  • Wedge Argument*