Hyperbaric hydrogen therapy: a possible treatment for cancer

Science. 1975 Oct 10;190(4210):152-4. doi: 10.1126/science.1166304.


Hairless albino mice with squamous cell carcinoma were exposed to a mixture of 2.5 percent oxygen and 97.5 percent hydrogen at a total pressure of 8 atmospheres for periods up to 2 weeks in order to see if a free radical decay catalyzer, such as hydrogen, would cause a regression of the skin tumors. Marked aggression of the tumors was found, leading to the possibility that hyperbaric hydrogen therapy might also prove to be of significance in the treatment of other types of cancer.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Atmosphere Exposure Chambers
  • Atmospheric Pressure
  • Carcinoma, Squamous Cell / therapy*
  • Free Radicals
  • Hydrogen / therapeutic use*
  • Mice
  • Neoplasms, Experimental / therapy
  • Skin Neoplasms / therapy*


  • Free Radicals
  • Hydrogen