Studies on polyamine biosynthesis in Euglena gracilis

Biochim Biophys Acta. 1979 Nov 22;565(1):199-207. doi: 10.1016/0005-2787(79)90096-0.


Euglene gracilis (strain Z) was found to contain five polyamines which could be separated by high-pressure cation-exchange chromatography. 1,3-Diaminopropane, putrescine, norspermidine (N-(3-aminopropyl)-1,3-diaminopropane), spermidine and norspermine (N,N'-bis(aminopropyl)-1,3-diaminopropane) were identified. Biosynthesis of putrescine in E. gracilis proceeds through decarboxylation of L-ornithine, no arginine decarboxylase (EC activity could be detected. The properties of the enzymes ornithine decarboxylase (EC and S-adenosylmethionine decarboxylase (EC in this alga were found to be similar to those of the enzymes isolated from animal tissues or yeast cells. A bioxynthetic scheme is proposed which relates the different polyamines occurring in E. gracilis.

MeSH terms

  • Adenosylmethionine Decarboxylase / metabolism
  • Animals
  • Euglena gracilis / metabolism*
  • Models, Chemical
  • Ornithine Decarboxylase / metabolism
  • Polyamines / biosynthesis*
  • Spermidine / analogs & derivatives
  • Spermidine / biosynthesis
  • Spermine / analogs & derivatives
  • Spermine / biosynthesis


  • Polyamines
  • Spermine
  • norspermine
  • norspermidine
  • Ornithine Decarboxylase
  • Adenosylmethionine Decarboxylase
  • Spermidine