Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease

Neurology. 2001 Oct 23;57(8):1497-9. doi: 10.1212/wnl.57.8.1497.


The authors studied the accuracy of clinical diagnosis of idiopathic PD (IPD) in 100 consecutive clinically diagnosed cases that came to neuropathological examination. Ninety fulfilled pathologic criteria for IPD. Ten were misdiagnosed: multiple system atrophy (six), progressive supranuclear palsy (two), post-encephalitic parkinsonism (one), and vascular parkinsonism (one). Assessment of the clinical features suggests that an accuracy of 90% may be the highest that can be expected using current diagnostic criteria.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Diagnosis, Differential
  • Diagnostic Errors*
  • Encephalitis / diagnosis
  • Female
  • Humans
  • Male
  • Middle Aged
  • Multiple System Atrophy / diagnosis
  • Parkinson Disease / diagnosis*
  • Supranuclear Palsy, Progressive / diagnosis