Use of the erythromycin breath test for in vivo assessments of cytochrome P4503A activity and dosage individualization

Clin Pharmacol Ther. 2001 Oct;70(4):305-10.
No abstract available

Publication types

  • Review

MeSH terms

  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / metabolism
  • Animals
  • Aryl Hydrocarbon Hydroxylases*
  • Breath Tests*
  • Carbon Dioxide / analysis
  • Carbon Radioisotopes
  • Cytochrome P-450 CYP3A
  • Cytochrome P-450 Enzyme System / biosynthesis
  • Cytochrome P-450 Enzyme System / metabolism*
  • Erythromycin* / blood
  • Erythromycin* / pharmacokinetics
  • Humans
  • Liver / enzymology
  • Liver / metabolism
  • Models, Chemical
  • Oxidoreductases, N-Demethylating / biosynthesis
  • Oxidoreductases, N-Demethylating / metabolism*
  • Sex Factors

Substances

  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Carbon Radioisotopes
  • Carbon Dioxide
  • Erythromycin
  • Cytochrome P-450 Enzyme System
  • Aryl Hydrocarbon Hydroxylases
  • Cytochrome P-450 CYP3A
  • Oxidoreductases, N-Demethylating