Objective: To evaluate the ImmunoCyt test--a urine-bound test for the detection of malignant transitional cells.
Patients and methods: ImmunoCyt was compared with the standard investigation at our hospital for bladder cancer--cystoscopy, cytological examination of bladder wash material and, if necessary, a histological examination. A voided urine sample was collected before cystoscopy. We investigated 121 patients; seven specimens could not be evaluated.
Results: Thirty-one of the 114 patients had a histologically proven urinary bladder carcinoma. All 31 cases were positive in the ImmunoCyt test. Twenty-six of the 83 negative cases were ImmunoCyt positive. The sensitivity was 100% and the specificity was 68.7%.
Conclusion: ImmunoCyt is easily applicable in a small laboratory and has high sensitivity and acceptable specificity.