Preliminary evaluation of the hypoglycemic effect of some Brazilian medicinal plants

Therapie. 2001 Jul-Aug;56(4):427-30.


The hypoglycemic effect of five Brazilian medicinal plants (Epidendrum monsenii, Marrubium vulgare, Rheedia gardneriana, Rubus imperialis and Wedelia paludosa) was studied on alloxan-induced diabetic rats. The extract of these plants was intragastrically administered to diabetic rats. The results showed that all plants studied (except R. gardneriana) significantly lowered the blood glucose. These results suggest that these four medicinal plants could be an adjuvant agent in the treatment of diabetes mellitus.

MeSH terms

  • Alloxan
  • Animals
  • Blood Glucose / analysis
  • Brazil
  • Chromatography, Thin Layer
  • Diabetes Mellitus, Experimental / blood
  • Diabetes Mellitus, Experimental / drug therapy*
  • Drug Evaluation, Preclinical
  • Hypoglycemic Agents / therapeutic use*
  • Male
  • Phytotherapy*
  • Plant Extracts / chemistry
  • Plant Extracts / therapeutic use*
  • Plants, Medicinal / chemistry*
  • Rats
  • Rats, Wistar


  • Blood Glucose
  • Hypoglycemic Agents
  • Plant Extracts
  • Alloxan