The spontaneous resorption of herniated cervical discs

J Clin Neurosci. 2001 Nov;8(6):542-6. doi: 10.1054/jocn.2000.0894.


The spontaneous resolution of herniated cervical discs has not been previously well documented. The authors analysed four cases who underwent spontaneous resolution of herniated cervical discs, and all other cases reported in the literature. A complex physiopathologic mechanism that includes the release of basic fibroblast grow factors, endothelial cell proliferation, chemotaxis of inflammatory cells into the disc fragment, foreign body inflammatory reaction, neovascularization and phagocytosis and accounts for the resorption of herniated discs is reviewed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Cervical Vertebrae
  • Female
  • Humans
  • Intervertebral Disc Displacement / pathology*
  • Magnetic Resonance Imaging
  • Male
  • Neck Pain / pathology
  • Radiculopathy / pathology
  • Remission, Spontaneous