Repeated pregnancies in patients with non-immunoglobulin a mesangioproliferative glomerulonephritis

Am J Nephrol. Sep-Oct 2001;21(5):378-82. doi: 10.1159/000046278.

Abstract

Aim: To analyze the effect of repeated pregnancies on underlying MesGN and see the reciprocal effect on maternal and fetal outcome.

Patients and methods: Pregnancy records of cases with histological diagnosis of MesGN were reviewed, and past medical histories recorded.

Results: Cesarean section (CS). Only two patients developed renal insufficiency after undergoing 5 and 11 pregnancies and follow-up of 9 and 20 years respectively.

Conclusion: The outcome of repeated pregnancies in patients with MesGN is comparable to normal deliveries. A higher incidence of pre-eclampsia, LBW babies and CS was noted in the post- compared to the pre-MesGN pregnancies. Repeated pregnancies do not influence the course of the MesGN.

MeSH terms

  • Adult
  • Chi-Square Distribution
  • Female
  • Glomerulonephritis, Membranoproliferative / physiopathology*
  • Humans
  • Pregnancy
  • Pregnancy Complications / physiopathology*
  • Pregnancy Outcome