The Paradox of Sympathetic Vasoconstriction in Exercising Skeletal Muscle

Exerc Sport Sci Rev. 2001 Oct;29(4):159-63. doi: 10.1097/00003677-200110000-00005.

Abstract

Is there sympathetic vasoconstriction in exercising skeletal muscle? Although convincing evidence exists that demonstrates vasoconstriction in active muscle, the proposition that the sympathetic nervous system constricts skeletal muscle during exercise poses a paradox, given the robust vasodilation that occurs in muscle during exercise. Ultimately, muscle perfusion is a balance between metabolic vasodilation and sympathetic vasoconstriction.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Blood Pressure / physiology
  • Cardiac Output
  • Exercise / physiology*
  • Humans
  • Kidney / blood supply
  • Muscle, Skeletal / physiology*
  • Regional Blood Flow
  • Sympathetic Nervous System / physiology*
  • Vasoconstriction / physiology*