Long-Term outcome of neonatal Citrobacter koseri (diversus) meningitis treated with imipenem/meropenem and surgical drainage

Infection. 2001 Oct;29(5):280-2. doi: 10.1007/s15010-001-1136-4.

Abstract

Neonatal Citrobacter koseri (diversus) meningitis is often complicated by the formation of brain abscesses and has a poor neurological outcome with seizures, mental retardation and paresis as sequelae in 50% of the cases. As there is emerging resistance to ampicillin, gentamicin and third-generation cephalosporins, we attempted to treat this infection with carbapenems. Carbapenems in combination with cefotaxime and surgical drainage may play an important role in treating C. koseri meningitis.

Publication types

  • Case Reports

MeSH terms

  • Carbapenems / therapeutic use*
  • Cefotaxime / therapeutic use*
  • Cephalosporins / therapeutic use*
  • Citrobacter / isolation & purification
  • Citrobacter / pathogenicity*
  • Combined Modality Therapy
  • Drainage
  • Enterobacteriaceae Infections / drug therapy*
  • Enterobacteriaceae Infections / pathology
  • Enterobacteriaceae Infections / surgery
  • Female
  • Humans
  • Infant, Newborn
  • Meningitis, Bacterial / drug therapy*
  • Meningitis, Bacterial / pathology
  • Meningitis, Bacterial / surgery
  • Prognosis
  • Treatment Outcome

Substances

  • Carbapenems
  • Cephalosporins
  • Cefotaxime