Seroprevalence of Helicobacter pylori among the diabetic population in Bangladesh: a comparative serological study on the newly diagnosed and older diabetics

Bangladesh Med Res Counc Bull. 2001 Apr;27(1):9-18.

Abstract

This prospective study was designed to find out the prevalence of H. pylori infection among the diabetic population in Bangladesh with a comparison between the newly diagnosed and older diabetics. For this study 520 diabetic patients: 152 (29%) newly diagnosed and 368 (71%) older diabetics of both sexes (250 male, 270 female) with a mean age of 58.5 +/- 12.04 years (range 10-70 years), were selected randomly from out and in-patient departments of BIRDEM, Dhaka. Mean fasting and 2 hours post load blood glucose level of the studied population was 10.53 +/- 4.08 mmol/L and 18.35 +/- 9.44 mmol/L respectively. The mean duration of the newly diagnosed diabetics was 0.44 +/- 0.35 years (range 2 days-1 year) and 6.78 +/- 5.45 (range 1-30) years for the older diabetics. H. pylori infection was defined as a true positive ELISA test result of > 1.5 standard deviation above the cut-off values of 15 AU/ml for adults and 10 AU/ml for children for anti H. pylori IgG. Of the studied population 441 (84.8%)--132 newly diagnosed and 309 (83.96%) older diabetics were seropositive for H. pylori infection. No significant differences were observed between the newly diagnosed and older diabetics (86.84% Vs 83.96%; p > 0.05).

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Age Factors
  • Aged
  • Bangladesh / epidemiology
  • Blood Glucose / analysis
  • Child
  • Diabetes Complications*
  • Diabetes Mellitus / blood
  • Diabetes Mellitus / diagnosis
  • Dyspepsia / complications*
  • Dyspepsia / diagnosis
  • Dyspepsia / epidemiology*
  • Dyspepsia / immunology
  • Female
  • Helicobacter Infections / complications*
  • Helicobacter Infections / diagnosis
  • Helicobacter Infections / epidemiology*
  • Helicobacter Infections / immunology
  • Helicobacter pylori*
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Seroepidemiologic Studies
  • Sex Distribution
  • Socioeconomic Factors
  • Time Factors

Substances

  • Blood Glucose