Antioxidative components from the aerial parts of Lactuca scariola L

Arch Pharm Res. 2001 Oct;24(5):427-30. doi: 10.1007/BF02975189.

Abstract

The antioxidant activity of Lactuca scariola (Compositae) was investigated by measuring the radical scavenging effect on DPPH (1,1-diphenyl-2-picrylhydrazyl) radical. The methanolic extract of the aerial parts of Lactuca scariola showed strong radical scavenging activity. The EtOAc soluble fraction exhibited a stronger activity than the others, and was purified by silica gel and Sephadex LH-20 column chromatography. Quercetin-3-O-beta-D-glucopyranoside, luteolin-7-O-beta-D-glucopyranoside, luteolin, quercetin and kaempferol, together with 1beta,13-dihydrolactucin were isolated from the EtOAc soluble fraction as active ingredients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antioxidants / chemistry*
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Asteraceae / chemistry*
  • Bepridil / analogs & derivatives*
  • Bepridil / chemistry
  • Biphenyl Compounds
  • Chromatography, Liquid
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification
  • Free Radical Scavengers / pharmacology
  • Magnetic Resonance Spectroscopy
  • Picrates*
  • Plant Extracts / analysis
  • Solvents
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Free Radical Scavengers
  • Picrates
  • Plant Extracts
  • Solvents
  • Bepridil
  • 1,1-diphenyl-2-picrylhydrazyl