A case of fetal parvovirus B19 myocarditis, terminal cardiac heart failure, and perinatal heart transplantation

Fetal Diagn Ther. Nov-Dec 2001;16(6):427-32. doi: 10.1159/000053953.


We report a case of fetal cardiomegaly secondary to myocarditis as a result of intrauterine parvovirus B19 infection. The fetus was delivered through caesarean section because of increasing deterioration of cardiac function at 33 + 3 weeks with reverse flow in the ductus venosus. Four weeks later, a cardiac transplantation was carried out because of therapy-resistant dilative cardiomyopathy. This case shows that fetal parvovirus B19 infection may occur without anemia and myocarditis and does not always result in spontaneous reformation of a dilated heart and normal recovery. It may become the determining prognostic factor for the child.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cardiomyopathy, Dilated / etiology*
  • Cardiomyopathy, Dilated / surgery*
  • Female
  • Fetal Diseases / virology*
  • Gestational Age
  • Heart Transplantation*
  • Humans
  • Myocarditis / complications
  • Myocarditis / diagnostic imaging
  • Myocarditis / virology*
  • Parvoviridae Infections / virology*
  • Parvovirus B19, Human*
  • Pregnancy
  • Ultrasonography, Prenatal