Neuronal potential and lineage determination by neural stem cells
- PMID: 11698181
- DOI: 10.1016/s0955-0674(00)00269-6
Neuronal potential and lineage determination by neural stem cells
Abstract
How do neural stem cells ensure that they give rise to the right number and type of neurons at the right time? Over the past year several regulatory mechanisms have been identified, including promotion of neurogenesis by proneural bHLH genes, instruction of gliogenesis by Notch, and cell-intrinsic changes in the neurogenic capacity of stem cells in culture and in vivo.
Similar articles
-
SoxB1 transcription factors and Notch signaling use distinct mechanisms to regulate proneural gene function and neural progenitor differentiation.Development. 2008 May;135(10):1843-51. doi: 10.1242/dev.020180. Epub 2008 Apr 16. Development. 2008. PMID: 18417619
-
Mechanisms regulating lineage diversity during mammalian cerebral cortical neurogenesis and gliogenesis.Results Probl Cell Differ. 2002;39:27-52. doi: 10.1007/978-3-540-46006-0_2. Results Probl Cell Differ. 2002. PMID: 12357985 Review.
-
Lineage analysis of quiescent regenerative stem cells in the adult brain by genetic labelling reveals spatially restricted neurogenic niches in the olfactory bulb.Eur J Neurosci. 2009 Jul;30(1):9-24. doi: 10.1111/j.1460-9568.2009.06798.x. Epub 2009 Jun 25. Eur J Neurosci. 2009. PMID: 19558606
-
Cell-intrinsic differences between stem cells from different regions of the peripheral nervous system regulate the generation of neural diversity.Neuron. 2002 Aug 15;35(4):643-56. doi: 10.1016/s0896-6273(02)00825-5. Neuron. 2002. PMID: 12194865
-
Timing is everything: making neurons versus glia in the developing cortex.Neuron. 2007 May 3;54(3):357-69. doi: 10.1016/j.neuron.2007.04.019. Neuron. 2007. PMID: 17481390 Review.
Cited by
-
The realized niche of adult neural stem cells.Stem Cell Rev. 2006;2(3):233-40. doi: 10.1007/s12015-006-0051-6. Stem Cell Rev. 2006. PMID: 17625259 Review.
-
Mechanisms and Functional Significance of Stroke-Induced Neurogenesis.Front Neurosci. 2015 Dec 8;9:458. doi: 10.3389/fnins.2015.00458. eCollection 2015. Front Neurosci. 2015. PMID: 26696816 Free PMC article. Review.
-
BMP2 promotes the differentiation of neural stem cells into dopaminergic neurons in vitro via miR-145-mediated upregulation of Nurr1 expression.Am J Transl Res. 2016 Sep 15;8(9):3689-3699. eCollection 2016. Am J Transl Res. 2016. PMID: 27725851 Free PMC article.
-
The novel gene asb11: a regulator of the size of the neural progenitor compartment.J Cell Biol. 2006 Aug 14;174(4):581-92. doi: 10.1083/jcb.200601081. Epub 2006 Aug 7. J Cell Biol. 2006. PMID: 16893969 Free PMC article.
-
Brain-derived neurotrophic factor participates in determination of neuronal laminar fate in the developing mouse cerebral cortex.J Neurosci. 2006 Dec 20;26(51):13218-30. doi: 10.1523/JNEUROSCI.4251-06.2006. J Neurosci. 2006. PMID: 17182772 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Miscellaneous
