Meiosis: how to create a specialized cell cycle

Curr Opin Cell Biol. 2001 Dec;13(6):770-7. doi: 10.1016/s0955-0674(00)00282-9.


During the meiotic cell cycle, a single round of DNA replication precedes two nuclear divisions. Recent work has shown that the proteins controlling the mitotic cell cycle are either replaced by homologous proteins only expressed during the meiotic cell cycle or modulated by meiosis-specific factors to bring about this specialized cell cycle.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Cycle*
  • Centromere / physiology
  • Chromatids / genetics
  • Chromosome Segregation
  • G1 Phase
  • G2 Phase
  • Kinetochores / physiology
  • Meiosis*
  • Models, Genetic
  • Saccharomyces cerevisiae / cytology
  • Saccharomyces cerevisiae / genetics
  • Schizosaccharomyces / cytology
  • Schizosaccharomyces / genetics
  • Sister Chromatid Exchange