A signal/noise analysis of quasi-static MR elastography

IEEE Trans Med Imaging. 2001 Nov;20(11):1183-7. doi: 10.1109/42.963821.

Abstract

In quasi-static magnetic resonance elastography, strain images of a tissue or material undergoing deformation are produced. In this paper, the signal/noise (S/N) ratio [SNR] of elastographic strain images, as measured by a phase-contrast technique, is analyzed. Experiments are conducted to illustrate how diffusion-mediated signal attenuation limits maximum strain SNR in small displacement cases, while the imaging point-spread function limits large displacement cases. A simple theoretical treatment agrees well with experiments and shows how an optimal displacement encoding moment can be predicted for a given experimental set of parameters to achieve a maximum strain SNR. A further experiment demonstrates how the limitation on strain SNR posed by the imaging point-spread function may potentially be overcome.

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Diffusion
  • Elasticity
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Models, Theoretical
  • Noise*
  • Predictive Value of Tests
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted*