Altered Nuclear Transport and the Most Selfish of Genes

Dev Cell. 2001 Sep;1(3):311-3. doi: 10.1016/s1534-5807(01)00050-8.

Abstract

The Segregation Distorter System in Drosophila is one of the best-known and genetically characterized systems of meiotic drive. A recent paper by Kusano et al. (2001) provides a key molecular insight into the molecular mechanism by which one chromosome can ensure the destruction of its partner.

Publication types

  • Comment

MeSH terms

  • Active Transport, Cell Nucleus
  • Animals
  • Cell Nucleus / metabolism*
  • Chromosome Segregation*
  • Drosophila Proteins*
  • Drosophila melanogaster / genetics*
  • Drosophila melanogaster / physiology
  • Female
  • GTPase-Activating Proteins / genetics
  • GTPase-Activating Proteins / metabolism*
  • Genes, Insect
  • Insect Proteins / genetics
  • Insect Proteins / metabolism
  • Male
  • Meiosis*
  • Repetitive Sequences, Nucleic Acid

Substances

  • Drosophila Proteins
  • GTPase-Activating Proteins
  • Insect Proteins
  • RanGAP protein, Drosophila