A 27-year follow-up of patients with borderline personality disorder

Compr Psychiatry. Nov-Dec 2001;42(6):482-7. doi: 10.1053/comp.2001.26271.


Sixty-four patients with borderline personality disorder (BPD) were followed up for a mean of 27 years. Outcome was assessed using the Diagnostic Interview for Borderlines, Revised (DIB-R); the Schedule for DSM-III-R Diagnosis (SCID); Global Assessment of Functioning (GAF); the Symptom Check List-90 (SCL-90); and the Social Adjustment Scale (SAS-SR). Most patients showed significant improvement as compared to a previous 15-year follow-up, with only five currently meeting criteria for BPD. Mean GAF score was 63.3, mean SCL-90 raw score was 0.7, and mean SAS-SR score was 2.0. Fourteen subjects met SCID criteria for dysthymia, and this subgroup had a significantly poorer outcome on all measures. The total percentage of suicides from the original cohort has reached 10.3%, with 18.2% of all patients now deceased.

MeSH terms

  • Borderline Personality Disorder / diagnosis
  • Borderline Personality Disorder / epidemiology*
  • Borderline Personality Disorder / psychology*
  • Cohort Studies
  • Comorbidity
  • Dysthymic Disorder / epidemiology
  • Female
  • Follow-Up Studies
  • Humans
  • Interview, Psychological
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care
  • Suicide
  • Surveys and Questionnaires