Pathogenesis of rotavirus diarrhea

Microbes Infect. 2001 Nov;3(13):1145-56. doi: 10.1016/s1286-4579(01)01475-7.

Abstract

Rotavirus diarrhea is a major cause of infantile gastroenteritis worldwide. This review is mainly devoted to the effects of Rotavirus on intestinal epithelial transport and to the pathophysiological mechanisms proposed to underlie the intestinal fluid secretion caused by the virus.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aging
  • Biological Transport
  • Diarrhea / metabolism
  • Diarrhea / pathology
  • Diarrhea / physiopathology*
  • Diarrhea / virology*
  • Diarrhea, Infantile / metabolism
  • Diarrhea, Infantile / pathology
  • Diarrhea, Infantile / physiopathology
  • Diarrhea, Infantile / virology
  • Humans
  • Infant
  • Intestinal Mucosa / blood supply
  • Intestinal Mucosa / innervation
  • Intestinal Mucosa / physiopathology
  • Intestinal Mucosa / virology
  • Models, Biological
  • Rotavirus / isolation & purification
  • Rotavirus / physiology*
  • Rotavirus Infections / metabolism
  • Rotavirus Infections / pathology
  • Rotavirus Infections / physiopathology*
  • Rotavirus Infections / virology