Voltage-gated sodium channels

Curr Opin Pharmacol. 2001 Feb;1(1):17-21. doi: 10.1016/s1471-4892(01)00007-8.


Increased knowledge of the molecular diversity of sodium channel alpha- and beta-subunits, and their distribution of expression have been highlights of the past year. The development of subtype-specific channel blockers remains elusive, but the discovery of selective inhibitors such as mu-conotoxins promises useful antagonists in the near future.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Humans
  • Ion Channel Gating / drug effects
  • Ion Channel Gating / physiology*
  • Signal Transduction / drug effects
  • Signal Transduction / physiology
  • Sodium Channels / drug effects
  • Sodium Channels / physiology*


  • Sodium Channels