Tissue-specific effects of peptides

Bull Exp Biol Med. 2001 Aug;132(2):807-8. doi: 10.1023/a:1013058701974.

Abstract

Synthetic peptides (cytogens) Cortagen, Epithalon, Livagen, and Vilon stimulated the growth of explants from rat brain cortex, subcortical structures, liver, and thymus, respectively, in organotypic cultures. These peptides produced tissue-specific effects: they stimulated the growth of explants from tissues, whose cytomedins (peptide complexes) were used for chemical synthesis.

MeSH terms

  • Animals
  • Cell Division / drug effects
  • Cerebral Cortex / cytology
  • Cerebral Cortex / drug effects
  • Growth Substances / pharmacology*
  • Liver / cytology
  • Liver / drug effects
  • Organ Culture Techniques
  • Organ Specificity
  • Peptides / pharmacology*
  • Pineal Gland / cytology
  • Pineal Gland / drug effects
  • Rats
  • Rats, Wistar
  • Thymus Gland / cytology
  • Thymus Gland / drug effects

Substances

  • Growth Substances
  • Peptides