From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

Nat Rev Neurosci. 2001 Nov;2(11):806-19. doi: 10.1038/35097565.
No abstract available

Publication types

  • Review

MeSH terms

  • Amyotrophic Lateral Sclerosis / genetics*
  • Amyotrophic Lateral Sclerosis / physiopathology*
  • Amyotrophic Lateral Sclerosis / therapy
  • Animals
  • Astrocytes / physiology
  • Caspase 3
  • Caspases / metabolism
  • Cell Death
  • Copper / metabolism
  • Endothelial Growth Factors / genetics
  • Endothelial Growth Factors / metabolism
  • Humans
  • Lymphokines / genetics
  • Lymphokines / metabolism
  • Models, Molecular
  • Models, Neurological
  • Motor Neurons / physiology*
  • Neurofilament Proteins / genetics
  • Neurofilament Proteins / metabolism
  • Oxidation-Reduction
  • Protein Structure, Tertiary
  • Superoxide Dismutase / chemistry
  • Superoxide Dismutase / genetics*
  • Superoxide Dismutase / metabolism
  • Superoxide Dismutase-1
  • Vascular Endothelial Growth Factor A
  • Vascular Endothelial Growth Factors
  • Zinc / metabolism

Substances

  • Endothelial Growth Factors
  • Lymphokines
  • Neurofilament Proteins
  • SOD1 protein, human
  • Vascular Endothelial Growth Factor A
  • Vascular Endothelial Growth Factors
  • Copper
  • Superoxide Dismutase
  • Superoxide Dismutase-1
  • CASP3 protein, human
  • Caspase 3
  • Caspases
  • Zinc