Smoking cessation following CT screening for early detection of lung cancer

Prev Med. 2001 Dec;33(6):613-21. doi: 10.1006/pmed.2001.0935.


Background: This study was conducted to assess the impact of lung cancer screening participation on smoking cessation.

Methods: Individuals (n = 134) who reported active smoking at the time of enrollment in our Early Lung Cancer Action Program (ELCAP) completed a brief, follow-up telephone interview assessing any changes in smoking patterns following lung cancer screening. Using logistic regression, we estimated the probability of decreasing or quitting smoking using each enrollee's background information and computed tomography (CT) scan results.

Results: Most survey respondents (74%) agreed that participation in the ELCAP increased their motivation for quitting smoking. In terms of self-reported changes in smoking behavior, 31 (23%) reported that they had quit and 35 (27%) decreased their smoking patterns. Several significant covariates of smoking cessation were identified: perceived benefit of quitting (OR 4.02), cancer anxiety (OR 2.49), younger age (OR 2.47), and abnormal CT finding (1.97).

Conclusions: Our analyses suggest that low-dose helical CT scanning may serve as a strong catalyst for smoking cessation and that delivery of effective smoking cessation interventions along with CT scanning represents a potential opportunity to increase the overall cancer prevention benefit of lung cancer screening.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aged
  • Female
  • Humans
  • Logistic Models
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / etiology
  • Lung Neoplasms / prevention & control
  • Male
  • Mass Screening
  • Motivation*
  • Smoking / adverse effects
  • Smoking Cessation / psychology*
  • Tomography, X-Ray Computed