Evolutionary perspective on innate immune recognition

J Cell Biol. 2001 Nov 26;155(5):705-10. doi: 10.1083/jcb.200107040. Epub 2001 Nov 26.

Abstract

Analysis of human and Drosophila genomes demonstrates an ancient origin of innate immunity and the diversity of the mechanisms of innate immune recognition.

Publication types

  • Review

MeSH terms

  • Adaptor Proteins, Signal Transducing*
  • Animals
  • Biological Evolution*
  • Carrier Proteins / immunology
  • Carrier Proteins / metabolism
  • Drosophila / genetics*
  • Drosophila / immunology
  • Drosophila Proteins*
  • Genome, Human
  • Humans
  • Immunity, Innate / physiology*
  • Membrane Glycoproteins / immunology
  • Membrane Glycoproteins / metabolism
  • Nod1 Signaling Adaptor Protein
  • Receptors, Cell Surface / immunology
  • Receptors, Cell Surface / metabolism
  • Signal Transduction / physiology*
  • Toll-Like Receptor 5
  • Toll-Like Receptors

Substances

  • Adaptor Proteins, Signal Transducing
  • Carrier Proteins
  • Drosophila Proteins
  • Membrane Glycoproteins
  • NOD1 protein, human
  • Nod1 Signaling Adaptor Protein
  • Receptors, Cell Surface
  • Toll-Like Receptor 5
  • Toll-Like Receptors
  • tehao protein, Drosophila