Diagnosis of culture-negative female genital tract tuberculosis with peritoneal involvement by polymerase chain reaction

J Reprod Med. 2001 Oct;46(10):929-32.


Background: Female genital tract tuberculosis (TB) is a common cause of infertility in developing countries. It is a paucibacillary form of the disease of which smears and cultures are usually negative.

Case: We were able to use polymerase chain reaction (PCR) amplification of Mycobacterium tuberculosis DNA to support a clinical and histologic diagnosis of a typical case of culture negative female genital tract TB.

Conclusion: PCR may be a useful adjunct to diagnostic efforts in gynecologic tuberculosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • DNA, Bacterial / genetics*
  • Diagnosis, Differential
  • False Negative Reactions
  • Female
  • Humans
  • Mycobacterium tuberculosis / genetics*
  • Mycobacterium tuberculosis / pathogenicity
  • Peritoneum / microbiology
  • Polymerase Chain Reaction*
  • Tuberculosis, Female Genital / diagnosis*
  • Tuberculosis, Female Genital / genetics*


  • DNA, Bacterial