Diabetes is a serious and costly disorder. The economic impact on the health care delivery system in the United States is extremely large, and the cost to individual affected patients in terms of health status, productivity, and quality of life is immeasurable. Population-based DM initiatives are undergoing extensive testing and application. These strategies have been demonstrated to enhance the care delivered to diabetic patients, improve clinical outcomes and quality of life, and reduce the financial toll of managing the disease. These gains are very valuable to the MCO, which is concerned with providing optimal cost-effective patient care in a systematic fashion.