Genome-wide analysis of Sox genes in Drosophila melanogaster

Mech Dev. 2001 Dec;109(2):371-5. doi: 10.1016/s0925-4773(01)00529-9.


Genes of the Sox family encode evolutionarily conserved HMG box containing transcription factors, which play key roles in various events of cell determination/differentiation during development. The total number of Sox genes in Drosophila melanogaster was estimated to be eight, after classical molecular cloning approaches and exhaustive screening of the complete Drosophila genome. Here we report the embryonic and larval expression pattern of four previously uncharacterized Sox genes, through antibody staining and in situ hybridization experiments.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cloning, Molecular
  • DNA-Binding Proteins / biosynthesis
  • DNA-Binding Proteins / genetics
  • Databases as Topic
  • Drosophila Proteins / biosynthesis
  • Drosophila melanogaster / genetics*
  • Genome*
  • High Mobility Group Proteins / biosynthesis
  • In Situ Hybridization
  • Multigene Family
  • Open Reading Frames
  • SOX Transcription Factors
  • Time Factors
  • Tissue Distribution
  • Transcription Factors / biosynthesis
  • Transcription Factors / genetics*


  • D protein, Drosophila
  • DNA-Binding Proteins
  • Drosophila Proteins
  • High Mobility Group Proteins
  • SOX Transcription Factors
  • SoxN protein, Drosophila
  • Transcription Factors