[Giant aneurysms of the pulmonary artery and peripheral venous thrombosis (Hughes-Stovin syndrome): regression with immunosuppressant therapy]

Arch Bronconeumol. 2001 Dec;37(11):508-10. doi: 10.1016/s0300-2896(01)75131-9.
[Article in Spanish]

Abstract

We report the case of a young Afro-Caribbean patient who complained of dry cough and low-grade fever. A chest film upon admission showed bilateral hilar masses in the lungs, which a CT scan with contrast medium confirmed were giant aneurysms of the pulmonary artery. The most relevant past history was deep venous thrombosis six months before admission. Hughes-Stovin syndrome was diagnosed and treatment was started with prednisolone and azathioprine. A scan 6 months after treatment ended showed the aneurysms had disappeared. Hughes-Stovin syndrome is characterized by pulmonary artery aneurysms and peripheral deep venous thromboses. Severe lung complications can include hemoptysis and thromboses inside the aneurysms. Hughes-Stovin syndrome has been considered a variety of BehCet's disease.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Aneurysm / complications
  • Aneurysm / drug therapy*
  • Anti-Inflammatory Agents / therapeutic use*
  • Azathioprine / therapeutic use*
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Male
  • Peripheral Vascular Diseases / complications
  • Peripheral Vascular Diseases / drug therapy*
  • Prednisolone / therapeutic use*
  • Pulmonary Artery*
  • Remission Induction
  • Syndrome
  • Venous Thrombosis / complications
  • Venous Thrombosis / drug therapy*

Substances

  • Anti-Inflammatory Agents
  • Immunosuppressive Agents
  • Prednisolone
  • Azathioprine